Separating Thalassemia Trait and Iron Deficiency by Even Simpler Inspection

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Separating thalassemia trait and iron deficiency by even simpler inspection.

To the Editor I read with interest the correspondence relating to recent articles published in the Journal describing mathematical approaches to the differentiation of thalassemia trait (TT) and iron deficiency anemia (IDA). 1-3 I found this and the accompanying authors' responses to be thoughtful and informative. There has been a clear revival of interest in the application of discriminant fun...

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Iron-deficiency anemia and thalassemia trait differentiated by simple hematological tests and serum iron concentrations.

The diagnostic value of common hematology tests in differentiating between thalassemia trait and iron-deficiency anemia (IDA) was assessed. Serum iron concentration was included in a second stage of the diagnostic model and its predictive contribution was determined. After applying discriminant analysis to the data, minimization of Wilks's lambda (lambda) criterion was used to select the best p...

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Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices

OBJECTIVE We aimed at finding out reliable parameter in the differentiation of iron deficiency anemia (IDA) and beta-thalassemia trait (β-TT) in the adult population subjected to Saudi Arabian Premarital Screening Program. METHODS A total of 620 adults (age range 21-36 years) reported during February 2012 to November 2012. Tests for serum iron and ferritin were carried out in individuals show...

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Automated measurement of red blood cell microcytosis and hypochromia in iron deficiency and beta-thalassemia trait.

Some routine red blood cell (RBC) measurements and indexes (count, mean volume, volume dispersion, and mean hemoglobin [HGB] concentration) can be used to differentiate iron deficiency from heterozygous beta-thalassemia. A number of formulas that incorporate two or more of these measurements have been described to amplify such differences. The H*1 hematology analyzer directly measures volume an...

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Erythrocyte Catalase Activity in More Frequent Microcytic Hypochromic Anemia: Beta-Thalassemia Trait and Iron Deficiency Anemia

Most common microcytic hypochromic anemias are iron deficiency anemia (IDA) and β-thalassemia trait (BTT), in which oxidative stress (OxS) has an essential role. Catalase causes detoxification of H2O2 in cells, and it is an indispensable antioxidant enzyme. The study was designed to measure erythrocyte catalase activity (ECAT) in patients with IDA (10) or BTT (21), to relate it with thalassemia...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2009

ISSN: 1943-7722,0002-9173

DOI: 10.1309/ajcporrcp16wilsb